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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSPB6
All Species:
36.97
Human Site:
Y121
Identified Species:
90.37
UniProt:
O14558
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14558
NP_653218.1
160
17136
Y121
A
R
E
F
H
R
R
Y
R
L
P
P
G
V
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
P02488
172
19774
Y118
S
R
E
F
H
R
R
Y
R
L
P
S
N
V
D
Dog
Lupus familis
XP_541688
162
17317
Y121
A
R
E
F
H
R
R
Y
R
L
P
S
G
V
D
Cat
Felis silvestris
Mouse
Mus musculus
Q5EBG6
162
17502
Y121
A
R
E
F
H
R
R
Y
R
L
P
P
G
V
D
Rat
Rattus norvegicus
P97541
162
17486
Y121
A
R
E
F
H
R
R
Y
R
L
P
P
G
V
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511816
173
19858
Y118
S
R
E
F
H
R
R
Y
R
L
P
S
N
V
D
Chicken
Gallus gallus
P02504
173
19769
Y118
S
R
E
F
H
R
R
Y
R
L
P
A
N
V
D
Frog
Xenopus laevis
NP_001086479
168
18812
Y123
S
R
E
F
H
R
R
Y
K
I
P
P
T
V
N
Zebra Danio
Brachydanio rerio
NP_694482
173
19695
Y119
S
R
E
F
H
R
R
Y
R
L
P
S
N
V
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_523827
187
21290
Y126
S
R
Q
F
S
R
R
Y
Q
L
P
S
D
V
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
42.4
91.9
N.A.
88.2
89.5
N.A.
43.3
42.7
54.7
42.7
N.A.
37.4
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
61
95
N.A.
91.9
93.2
N.A.
63
65.3
69.6
58.9
N.A.
51.8
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
80
93.3
N.A.
100
100
N.A.
80
80
66.6
80
N.A.
53.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
86.6
93.3
N.A.
100
100
N.A.
86.6
86.6
93.3
86.6
N.A.
80
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
40
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
80
% D
% Glu:
0
0
90
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
100
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
40
0
0
% G
% His:
0
0
0
0
90
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
90
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
40
0
20
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
100
40
0
0
0
% P
% Gln:
0
0
10
0
0
0
0
0
10
0
0
0
0
0
0
% Q
% Arg:
0
100
0
0
0
100
100
0
80
0
0
0
0
0
0
% R
% Ser:
60
0
0
0
10
0
0
0
0
0
0
50
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
100
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
100
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _